The Branches are a core component of the LICR global network. The number of staff at each is intended to be sufficiently large for the Branch's groups to address complex biological problems related to cancer with a critical mass of interactive scientists having expertise in several disciplines. Each of the Institute's nine Branches is physically and functionally associated with a university or research institute and a non-for-profit hospital. This arrangement guarantees an academic environment conducive to laboratory discovery, provides access to local institutional resources and expertise, and is designed to facilitate the rapid transition of laboratory discoveries to clinical application.
Situated in Brussels (Belgium), and led by Dr. Thierry Boon, the Brussels Branch specializes in cancer genetics and cancer immunology, and applies this knowledge to the identification and development of immunotherapies for cancer.
Situated in Lausanne (Switzerland), and led by Dr. H. Robson MacDonald, the Lausanne Branch conducts research into basic and applied immunology in order to understand and develop therapies that harness the immune response for the treatment of human cancer.
Situated in Melbourne (Australia), and led by Dr. Antony Burgess, the Melbourne Branch aims to identify and characterize molecules that contribute to the tumorigenic state, in particular those molecules that can be exploited for cancer treatment.
Situated in Melbourne (Australia), and led by Dr. Andrew Scott, the Melbourne Center is focused on the translation of basic research discoveries into clinical therapies.
Situated in New York (USA), and led by Dr. Lloyd Old, the New York Branch focuses on the identification and characterization of suitable targets for, and the development of, antibody-based and vaccine-based immunotherapies for human cancer.
Situated in Oxford (UK), and led by Dr. Xin Lu, the Oxford Branch seeks to characterize metastasis, the spread of cancer, in order to identify new therapy targets.
Situated in San Diego (USA), and led by Dr. Webster Cavenee, the San Diego Branch focuses on the genetics, biochemistry, and cell biology of the nature, cause, regulation, order, and consequences of genetic changes that occur during the malignant progression of cancer.
Situated in São Paulo (Brazil), and led by Dr. Luisa L. Villa, the São Paulo Branch focuses on cancer genetics and cellular processes that determine the development of cancer, leading to the identification of diagnostic, prognostic, and therapeutic markers.
Situated in Stockholm (Sweden), and led by Dr. Thomas Perlmann, the Stockholm Branch focuses on errors in signal transduction that impair vital cellular functions and lead to cancer, with the aim of developing therapies that inhibit the aberrant signal transduction in cancer cells.
Situated in Uppsala (Sweden), and led by Dr. Carl-Henrik Heldin,
the Uppsala Branch seeks to elucidate the signal transduction pathways
that control growth, differentiation, motility, and apoptosis in
order to develop therapies against these processes in cancer cells.